Novel 7-Chloro-4-aminoquinoline-benzimidazole Hybrids as Inhibitors of Cancer Cells Growth: Synthesis, Antiproliferative Activity, in Silico ADME Predictions, and Docking

In this study, new 7-chloro-4-aminoquinoline-benzimidazole compounds were synthesized and characterized by NMR, MS, and elemental analysis. These novel hybrids differ in the type of linker and in the substituent on the benzimidazole moiety. Their antiproliferative activities were evaluated on one no...

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Bibliographic Details
Main Authors: Luka Krstulović, Marijana Leventić, Vesna Rastija, Kristina Starčević, Maja Jirouš, Ivana Janić, Maja Karnaš, Kornelija Lasić, Miroslav Bajić, Ljubica Glavaš-Obrovac
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/2/540