Artificial Intelligence-Powered Whole-Slide Image Analyzer Reveals a Distinctive Distribution of Tumor-Infiltrating Lymphocytes in Neuroendocrine Neoplasms

Artificial Intelligence-Powered Whole-Slide Image Analyzer Reveals a Distinctive Distribution of Tumor-Infiltrating Lymphocytes in Neuroendocrine Neoplasms

Despite the importance of tumor-infiltrating lymphocytes (TIL) and PD-L1 expression to the immune checkpoint inhibitor (ICI) response, a comprehensive assessment of these biomarkers has not yet been conducted in neuroendocrine neoplasm (NEN). We collected 218 NENs from multiple organs, including 190...

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Bibliographic Details
Main Authors: Hyung-Gyo Cho, Soo Ick Cho, Sangjoon Choi, Wonkyung Jung, Jiwon Shin, Gahee Park, Jimin Moon, Minuk Ma, Heon Song, Mohammad Mostafavi, Mingu Kang, Sergio Pereira, Kyunghyun Paeng, Donggeun Yoo, Chan-Young Ock, Seokhwi Kim
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Diagnostics
Subjects:
neuroendocrine neoplasm
tumor-infiltrating lymphocyte
artificial intelligence
PD-L1
biomarker
Online Access:https://www.mdpi.com/2075-4418/12/10/2340

Internet

https://www.mdpi.com/2075-4418/12/10/2340

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