An Update on Self-Amplifying mRNA Vaccine Development
This review will explore the four major pillars required for design and development of an saRNA vaccine: Antigen design, vector design, non-viral delivery systems, and manufacturing (both saRNA and lipid nanoparticles (LNP)). We report on the major innovations, preclinical and clinical data reported...
| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
MDPI AG
2021-01-01
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| coleção: | Vaccines |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2076-393X/9/2/97 |