The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA
Background: In our recent study using [U–13C3]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol (1,3PDO) and 3-hydroxypropionate (3HP) which were detected in the liver and blo...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | Metabolism Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589936821000104 |