The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA

The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA

Background: In our recent study using [U–13C3]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol (1,3PDO) and 3-hydroxypropionate (3HP) which were detected in the liver and blo...

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Bibliographic Details
Main Authors:	Eunsook S. Jin, Min H. Lee, Craig R. Malloy
Format:	Article
Language:	English
Published:	Elsevier 2021-03-01
Series:	Metabolism Open
Subjects:	1,3-Propanediol 3-Hydroxypropionate Gluconeogenesis Oxidative metabolism Aldehyde dehydrogenase Ketogenesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589936821000104

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