Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

The PIWI-interacting RNA (piRNA) pathway controls transposon expression in animal germ cells, thereby ensuring genome stability over generations. In Drosophila, piRNAs are intergenerationally inherited through the maternal lineage, and this has demonstrated importance in the specification of piRNA s...

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Bibliographic Details
Main Authors: Martin H Fabry, Federica A Falconio, Fadwa Joud, Emily K Lythgoe, Benjamin Czech, Gregory J Hannon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
chromatin
transposable elements
epigenetics
Drosophila
piRNA pathway
embryogenesis
Online Access:https://elifesciences.org/articles/68573

Internet

https://elifesciences.org/articles/68573

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