A 3’UTR-derived small RNA represses pneumolysin synthesis and facilitates pneumococcal brain invasion
Abstract Pneumolysin (Ply) of Streptococcus pneumoniae (pneumococcus) at relatively high and low levels facilitates pneumococcal invasion into the lung and brain, respectively; however, the regulatory mechanisms of Ply expression are poorly understood. Here, we find that a small RNA plyT, processed...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-06845-8 |