Serum-tolerant polymeric complex for stem-cell transfection and neural differentiation

Serum-tolerant polymeric complex for stem-cell transfection and neural differentiation

Abstract Mesenchymal stem cell (MSC) therapy holds promise in biomedical applications but faces challenges in efficient transfection without compromising cell viability. Here, we show a serum-tolerant MSC transfection nanotool, APOs@BP, composed of an apolipoprotein (APO) corona and a boronated poly...

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Bibliographic Details
Main Authors: Yi Jin, Guochen Han, Yuemei Gao, Hao Cheng, Chenhua Sun, Jiang Ni, Jianping Zhou, Huaqing Zhang, Yang Ding
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57278-8

Internet

https://doi.org/10.1038/s41467-025-57278-8

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