Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity

Opposing Effects of Interleukin-36γ and Interleukin-38 on Trained Immunity

Trained immunity is the process of long-term functional reprogramming (a <i>de facto</i> innate immune memory) of innate immune cells such as monocytes and macrophages after an exposure to pathogens, vaccines, or their ligands. The induction of trained immunity is mediated through epigen...

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Bibliographic Details
Main Authors: Lisa U. Teufel, Mihai G. Netea, Frank L. van de Veerdonk, Charles A. Dinarello, Leo A. B. Joosten, Rob J. W. Arts
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
IL-36
IL-38
innate immune memory
epigenetics
immunometabolism
Online Access:https://www.mdpi.com/1422-0067/24/3/2311

Internet

https://www.mdpi.com/1422-0067/24/3/2311

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