Possibility of selection against mtDNA mutations in tumors
<p>Abstract</p> <p>Several studies of tumors have revealed substantial numbers of clonally expanded somatic mutations in mitochondrial DNA (mtDNA), not observed in adjacent intact tissues. These findings were interpreted as indicating the involvement of mtDNA mutations in tumorigen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-09-01
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| Series: | Molecular Cancer |
| Subjects: | |
| Online Access: | http://www.molecular-cancer.com/content/4/1/36 |