Identifying USP1 Inhibitors with Allosteric Effect on Its Triple Catalytic Center through Virtual Screening
Previous studies have shown that downregulation of ubiquitin-specific protease 1 (USP1) can inhibit cell proliferation and promote apoptosis, indicating that targeting USP1 with drugs is a potential treatment for cancer, especially breast and ovarian cancer. In this study, we performed virtual scree...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2023-01-01
|
Series: | Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2023/9932996 |