Increased expression and altered methylation of HERVWE1 in the human placentas of smaller fetuses from monozygotic, dichorionic, discordant twins.

BACKGROUND: The human endogenous retroviral family W, Env(C7), member 1 gene (HERVWE1) is thought to participate in trophoblast cell fusion, and its expression is diminished in the placentas of singleton intrauterine growth-retarded pregnancies. However, there is limited information about the role o...

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Bibliographic Details
Main Authors: Yu Gao, Zhiming He, Zilian Wang, Yanmin Luo, Hongyu Sun, Yi Zhou, Linhuan Huang, Manchao Li, Qun Fang, Shiwen Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3310130?pdf=render