Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors

Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors

Pancreatic cancer (PC) is one of the most aggressive cancers in the world. Several extracellular factors are involved in its development and metastasis to distant organs. In PC, the protein Annexin A1 (ANXA1) appears to be overexpressed and may be identified as an oncogenic factor, also because it i...

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Bibliographic Details
Main Authors: Nunzia Novizio, Raffaella Belvedere, Emanuela Pessolano, Alessandra Tosco, Amalia Porta, Mauro Perretti, Pietro Campiglia, Amelia Filippelli, Antonello Petrella
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
extracellular vesicles
exosomes
annexin A1
pancreatic cancer
FPRs
Online Access:https://www.mdpi.com/2073-4409/9/12/2719

Internet

https://www.mdpi.com/2073-4409/9/12/2719

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