Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis

Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis

Abstract Background Autoimmune neuropathies can result in long-term disability and incomplete recovery, despite adequate first-line therapy. Kinesin-5 inhibition was shown to accelerate neurite outgrowth in different preclinical studies. Here, we evaluated the potential neuro-regenerative effects of...

Full description

Bibliographic Details
Main Authors: Felix Kohle, Robin Ackfeld, Franziska Hommen, Ines Klein, Martin K. R. Svačina, Christian Schneider, Gereon R. Fink, Mohammed Barham, David Vilchez, Helmar C. Lehmann
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Neuroinflammation
Subjects:
Experimental autoimmune neuritis
Guillain–Barré syndrome
Autoimmune neuropathy
Eg5
Monastrol
Neuroregeneration
Online Access:https://doi.org/10.1186/s12974-023-02822-w

Internet

https://doi.org/10.1186/s12974-023-02822-w

Similar Items