The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development: a potential novel therapy

The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development: a potential novel therapy

Aims: Therapeutic agents that prevent chondrocyte loss, extracellular matrix (ECM) degradation, and osteoarthritis (OA) progression are required. The expression level of epidermal growth factor (EGF)-like repeats and discoidin I-like domains-containing protein 3 (EDIL3) in damaged human cartilage is...

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Bibliographic Details
Main Authors: Mei-Feng Chen, Chih-Chien Hu, Yung-Heng Hsu, Yu-Chih Lin, Kai-Lin Chen, Steve W. N. Ueng, Yuhan Chang
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2023-12-01
Series:Bone & Joint Research
Subjects:
osteoarthritis
edil3
chondrocyte
extracellular matrix
cartilage
osteoarthritic changes
cartilage tissues
chondrocytes
antibodies
interleukin
aggrecan
pro-inflammatory cytokines
oarsi
subchondral bone plate
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.1212.BJR-2023-0087.R1

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https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.1212.BJR-2023-0087.R1

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