Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

Transcriptional profiling of paediatric ependymomas identifies prognostically significant groups

Abstract The majority of supratentorial ependymomas in children contain oncogenic fusions, such as ZFTA–RELA or YAP1‐MAMLD1. In contrast, posterior fossa (PF) ependymomas lack recurrent somatic mutations and are classified based on gene expression or methylation profiling into group A (PFA) and grou...

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Bibliographic Details
Main Authors: Maria Łastowska, Ewa Matyja, Anna Sobocińska, Bartosz Wojtaś, Magdalena Niemira, Anna Szałkowska, Adam Krętowski, Agnieszka Karkucińska‐Więckowska, Magdalena Kaleta, Maria Ejmont, Magdalena Tarasińska, Marta Perek‐Polnik, Bożenna Dembowska‐Bagińska, Maciej Pronicki, Wiesława Grajkowska, Joanna Trubicka
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:The Journal of Pathology: Clinical Research
Subjects:
ependymoma
molecular groups
NanoString
prognosis
transcriptional profiling
Online Access:https://doi.org/10.1002/cjp2.236

Internet

https://doi.org/10.1002/cjp2.236

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