CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions

CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions

Summary: CTCF is a predominant insulator protein required for three-dimensional chromatin organization. However, the roles of its insulation of enhancers in a 3D nuclear organization have not been fully explained. Here, we found that the CTCF DNA-binding domain (DBD) forms dynamic self-interacting c...

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Bibliographic Details
Main Authors: Rong Zhou, Kai Tian, Jie Huang, Wenjia Duan, Hongye Fu, Ying Feng, Hui Wang, Yongpeng Jiang, Yuanjun Li, Rui Wang, Jiazhi Hu, Hanhui Ma, Zhi Qi, Xiong Ji
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Molecular interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222012834

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http://www.sciencedirect.com/science/article/pii/S2589004222012834

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