Integrated analysis of DNA methylation and RNA transcriptome during in vitro differentiation of human pluripotent stem cells into retinal pigment epithelial cells.

Integrated analysis of DNA methylation and RNA transcriptome during in vitro differentiation of human pluripotent stem cells into retinal pigment epithelial cells.

Using the paradigm of in vitro differentiation of hESCs/iPSCs into retinal pigment epithelial (RPE) cells, we have recently profiled mRNA and miRNA transcriptomes to define a set of RPE mRNA and miRNA signature genes implicated in directed RPE differentiation. In this study, in order to understand t...

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Bibliographic Details
Main Authors: Zhenshan Liu, Rongfeng Jiang, Songtao Yuan, Na Wang, Yun Feng, Ganlu Hu, Xianmin Zhu, Kevin Huang, Jieliang Ma, Guotong Xu, Qinghuai Liu, Zhigang Xue, Guoping Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3956675?pdf=render

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http://europepmc.org/articles/PMC3956675?pdf=render

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