Akt Phosphorylation of Hepatitis C Virus NS5B Regulates Polymerase Activity and Hepatitis C Virus Infection

Akt Phosphorylation of Hepatitis C Virus NS5B Regulates Polymerase Activity and Hepatitis C Virus Infection

Hepatitis C virus (HCV) is a single-stranded RNA virus of positive polarity [ssRNA(+)] that replicates its genome through the activity of one of its proteins, called NS5B. This viral protein is responsible for copying the positive-polarity RNA genome into a negative-polarity RNA strand, which will b...

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Bibliographic Details
Main Authors: Rosario Sabariegos, Laura Albentosa-González, Blanca Palmero, Pilar Clemente-Casares, Eugenio Ramírez, Carlos García-Crespo, Isabel Gallego, Ana Isabel de Ávila, Celia Perales, Esteban Domingo, Antonio Mas
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Microbiology
Subjects:
HCV (hepatitis C)
NS5B (non-structural protein) polymerase
Akt
virus replication
phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.754664/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.754664/full

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