Dopamine D2 receptors in pyramidal neurons in the medial prefrontal cortex regulate social behavior

Dopamine D2 receptors in pyramidal neurons in the medial prefrontal cortex regulate social behavior

Drugs acting on dopamine D2 receptors are widely used for the treatment of several neuropsychiatric disorders, including schizophrenia and depression. Social deficits are a core symptom of these disorders. Pharmacological manipulation of dopamine D2 receptors (Drd2), a Gi-coupled subtype of dopamine...

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Bibliographic Details
Main Authors: Hao Chen, Xing-Xing Xiong, Shi-Yang Jin, Xiao-Ying He, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Gao, Yi-Hua Chen
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Pharmacological Research
Subjects:
Drd2
Social behavior
mPFC
Pyramidal neurons
Neural circuit
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823003985

Internet

http://www.sciencedirect.com/science/article/pii/S1043661823003985

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