Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates.

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that re-emerged in 2004 and has caused massive outbreaks in recent years. The lack of a licensed vaccine or treatment options emphasize the need to obtain more insight into the viral life cycle and CHIKV-host interactions. Infectious cDNA clon...

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Bibliographic Details
Main Authors: Florine E M Scholte, Ali Tas, Byron E E Martina, Paolo Cordioli, Krishna Narayanan, Shinji Makino, Eric J Snijder, Martijn J van Hemert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3731263?pdf=render