Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation
Endoplasmic reticulum aminopeptidases 1 and 2 (ERAP1 and ERAP2) play important roles in the generation of antigenic peptides presented by Major Histocompatibility Class I (MHCI) molecules and indirectly regulate adaptive immune responses. Although the discrete function of these enzymes has been exte...
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| Format: | Artikel |
| Sprache: | English |
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Frontiers Media S.A.
2022-04-01
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| Schriftenreihe: | Frontiers in Immunology |
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| Online Zugang: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.863529/full |