Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs

Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs

Fucosylated glycans critically regulate the physiological functions of proteins and cells. Alterations in levels of fucosylated glycans are associated with various diseases. For detection and functional modulation of fucosylated glycans, chemical biology approaches using fucose (Fuc) analogs are use...

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Bibliographic Details
Main Authors: Chenyu Ma, Hideyuki Takeuchi, Huilin Hao, Chizuko Yonekawa, Kazuki Nakajima, Masamichi Nagae, Tetsuya Okajima, Robert S. Haltiwanger, Yasuhiko Kizuka
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
fucose
fucosyltransferase
glycan
glycosylation
glycan labeling
click chemistry
Online Access:https://www.mdpi.com/1422-0067/21/17/6007

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https://www.mdpi.com/1422-0067/21/17/6007

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