Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs

Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs

Fucosylated glycans critically regulate the physiological functions of proteins and cells. Alterations in levels of fucosylated glycans are associated with various diseases. For detection and functional modulation of fucosylated glycans, chemical biology approaches using fucose (Fuc) analogs are use...

Full description

Bibliographic Details
Main Authors:	Chenyu Ma, Hideyuki Takeuchi, Huilin Hao, Chizuko Yonekawa, Kazuki Nakajima, Masamichi Nagae, Tetsuya Okajima, Robert S. Haltiwanger, Yasuhiko Kizuka
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	International Journal of Molecular Sciences
Subjects:	fucose fucosyltransferase glycan glycosylation glycan labeling click chemistry
Online Access:	https://www.mdpi.com/1422-0067/21/17/6007

Similar Items

Enzymes for N-Glycan Branching and Their Genetic and Nongenetic Regulation in Cancer
by: Yasuhiko Kizuka, et al.
Published: (2016-04-01)

The Diverse Contributions of Fucose Linkages in Cancer
by: Tyler S. Keeley, et al.
Published: (2019-08-01)

Anti-schistosomal immunity to core xylose/fucose in N-glycans
by: Nina Salinger Prasanphanich, et al.
Published: (2023-04-01)

Fucose as a nutrient ligand for Dikarya and a building block of early diverging lineages
by: Małgorzata Orłowska, et al.
Published: (2023-09-01)

Golgi fucosyltransferase 1 reveals its important role in α-1,4-fucose modification of N-glycan in CRISPR/Cas9 diatom Phaeodactylum tricornutum
by: Xihui Xie, et al.
Published: (2023-01-01)

Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A Review
by: Cristiana S de Macedo, et al.
Published: (2010-12-01)

7.342 Sweet Discoveries: Unraveling the Complex World of Sugars in Health and Disease, Fall 2014
by: Silverman, Julie M, et al.
Published: (2023)

Direct N-Glycosylation Profiling of Urine and Prostatic Fluid Glycoproteins and Extracellular Vesicles
by: Calvin R. K. Blaschke, et al.
Published: (2021-09-01)

Expanded Proteomic Survey of the Human Parasite Leishmania major Focusing on Changes in Null Mutants of the Golgi GDP-Mannose/Fucose/Arabinopyranose Transporter LPG2 and of the Mitochondrial Fucosyltransferase FUT1
by: Gloria Polanco, et al.
Published: (2022-12-01)

Assessment of serum L-fucose in brain tumor cases
by: Manjula S, et al.
Published: (2010-01-01)

Effects of L-fucose supplementation on the viability of cancer cell lines
by: Muhammad Alif Mazlan, et al.
Published: (2020-08-01)

Genomic reconstruction and features of glycosylation pathways in the apicomplexan Cryptosporidium parasites
by: Dongqiang Wang, et al.
Published: (2022-11-01)

Release of protein N-glycans by effectors of a Hofmann carboxamide rearrangement
by: Mumtaz Kasim, et al.
Published: (2022-09-01)

Prediction of Mortality in Patients on Peritoneal Dialysis Based on the Fibrinogen Mannosylation
by: Marko Baralić, et al.
Published: (2023-01-01)

Synthesis and glycosidation of building blocks of D-altrosamine
by: Mariya Novakova, et al.
Published: (2022-09-01)

Surface Engineering of HEK293 Cell-Derived Extracellular Vesicles for Improved Pharmacokinetic Profile and Targeted Delivery of IL-12 for the Treatment of Hepatocellular Carcinoma
by: Zhang J, et al.
Published: (2023-01-01)

Polysialic Acid in the Immune System
by: Tania M. Villanueva-Cabello, et al.
Published: (2022-02-01)

Glyco-Engineering Plants to Produce Helminth Glycoproteins as Prospective Biopharmaceuticals: Recent Advances, Challenges and Future Prospects
by: Alex van der Kaaij, et al.
Published: (2022-04-01)

Comparative Study of Fucose, Protein, Protein Bound Fucose and Protein Bound Hexose in Sera of Hyperprolactinemia Human Female and Healthy Female
by: W.F. Al-Taie, et al.
Published: (2017-05-01)

Mollusc N-glycosylation: Structures, Functions and Perspectives
by: Erika Staudacher
Published: (2021-12-01)

Anaplasma marginale Infection of Dermacentor andersoni Primary Midgut Cell Culture Is Dependent on Fucosylated Glycans
by: Rubikah Vimonish, et al.
Published: (2022-05-01)

Natural and Synthetic Sialylated Glycan Microarrays and Their Applications
by: Alyssa M. McQuillan, et al.
Published: (2019-09-01)

The Light-Controlled Release of 2-fluoro-<span style="font-variant: small-caps">l</span>-fucose, an Inhibitor of the Root Cell Elongation, from a nitrobenzyl-caged Derivative
by: Mathieu Carlier, et al.
Published: (2023-01-01)

Applying Acylated Fucose Analogues to Metabolic Glycoengineering
by: Julia Rosenlöcher, et al.
Published: (2015-11-01)

Radioactive fucose as a tool for studying glycoprotein secretion
by: A. Haddad
Published: (1998-02-01)

Genetic control of N-glycosylation of human blood plasma proteins
by: S. Zh. Sharapov, et al.
Published: (2023-06-01)

Glycan Modifications as Regulators of Stem Cell Fate
by: Raghad Alghazali, et al.
Published: (2024-01-01)

Lectins: an effective tool for screening of potential cancer biomarkers
by: Onn Haji Hashim, et al.
Published: (2017-09-01)

Databases and Bioinformatic Tools for Glycobiology and Glycoproteomics
by: Xing Li, et al.
Published: (2020-09-01)

Glycoengineering of Therapeutic Antibodies with Small Molecule Inhibitors
by: Shasha Li, et al.
Published: (2021-11-01)

Small molecule inhibitors of mammalian glycosylation
by: Karim Almahayni, et al.
Published: (2022-12-01)

Increased branching and sialylation of N-linked glycans correlate with an improved pharmacokinetic profile for BAY 81–8973 compared with other full-length rFVIII products
by: Teare JM, et al.
Published: (2019-03-01)

Glycan Analysis as Biomarkers for Testicular Cancer
by: Michal Hires, et al.
Published: (2019-10-01)

Limited Neonatal Carbohydrate-Specific Antibody Repertoire Consecutive to Partial Prenatal Transfer of Maternal Antibodies
by: Katharina Kappler, et al.
Published: (2020-10-01)

Adhesion of Helicobacter Species to the Human Gastric Mucosa: A Deep Look Into Glycans Role
by: Rita Matos, et al.
Published: (2021-05-01)

Roles for Golgi Glycans in Oogenesis and Spermatogenesis
by: Ayodele Akintayo, et al.
Published: (2019-06-01)

Advanced Plant-Based Glycan Engineering
by: Laura Montero-Morales, et al.
Published: (2018-06-01)

Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients’ Sera
by: Adrià Duran, et al.
Published: (2022-08-01)

Precision Glycan Supplementation Improves Gut Microbiota Diversity, Performance, and Disease Outbreak Resistance in Broiler Chickens
by: Edina Lobo, et al.
Published: (2023-12-01)

The Association of the Polymorphisms in the <i>FUT8</i>-Related Locus with the Plasma Glycosylation in Post-Traumatic Stress Disorder
by: Lucija Tudor, et al.
Published: (2023-03-01)