The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals

The existing zoonotic coronaviruses (CoVs) and viral genetic variants are important microbiological pathogens that cause severe disease in humans and animals. Currently, no effective broad-spectrum antiviral drugs against existing and emerging CoVs are available. The CoV main protease (M<sup>p...

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Bibliographic Details
Main Authors: Fenghua Wang, Cheng Chen, Zefang Wang, Xu Han, Peidian Shi, Kaixuan Zhou, Xiaomei Liu, Yunjie Xiao, Yan Cai, Jinhai Huang, Lei Zhang, Haitao Yang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/3/486