Revisiting the Roles of Filaggrin in Atopic Dermatitis

Revisiting the Roles of Filaggrin in Atopic Dermatitis

The discovery in 2006 that loss-of-function mutations in the filaggrin gene (<i>FLG</i>) cause ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology research community and shed new light on a skin protein that was first identified in 1981. However, a...

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Bibliographic Details
Main Authors: Verena Moosbrugger-Martinz, Corinne Leprince, Marie-Claire Méchin, Michel Simon, Stefan Blunder, Robert Gruber, Sandrine Dubrac
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
atopic dermatitis
filaggrin
epidermis
NMF
pH
microbiome
Online Access:https://www.mdpi.com/1422-0067/23/10/5318

Internet

https://www.mdpi.com/1422-0067/23/10/5318

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