Regulatory roles of alternative splicing at Ezh2 gene in mouse oocytes

Abstract Background Enhancer of zeste homologue 2 (EZH2), the core member of polycomb repressive complex 2 (PRC2), has multiple splicing modes and performs various physiological functions. However, function and mechanism of alternative splicing at Ezh2 exon 3 in reproduction are unknown. Methods We...

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Bibliographic Details
Main Authors: Shi-meng Guo, Xing-ping Liu, Qing Tian, Cai-feng Fei, Yi-ran Zhang, Zhi-ming Li, Ying Yin, Ximiao He, Li-quan Zhou
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-022-00962-x