Rheumatoid Arthritis and Cardio-Cerebrovascular Disease: A Mendelian Randomization Study

Significant genetic association exists between rheumatoid arthritis (RA) and cardiovascular disease. The associated mechanisms include common inflammatory mediators, changes in lipoprotein composition and function, immune responses, etc. However, the causality of RA and vascular/heart problems remai...

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Bibliographic Details
Main Authors: Shizheng Qiu, Meijie Li, Shunshan Jin, Haoyu Lu, Yang Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.745224/full