18 F-ASEM PET/MRI targeting alpha7-nicotinic acetylcholine receptor can reveal skeletal muscle denervation

18 F-ASEM PET/MRI targeting alpha7-nicotinic acetylcholine receptor can reveal skeletal muscle denervation

Abstract Background The increased expression of the nicotinic acetylcholine receptor (nAChR) in muscle denervation is thought to be associated with electrophysiological acetylcholine supersensitivity after nerve injury. Hence, we investigated the utility of the 18F-ASEM alpha7-nAChR targeting radiot...

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Bibliographic Details
Main Authors: Yong-il Kim, Seung Hak Lee, Jin Hwa Jung, Seog-Young Kim, Nare Ko, Sang Ju Lee, Seung Jun Oh, Jin-Sook Ryu, Dabin Ko, Won Kim, Kyunggon Kim
Format: Article
Language:English
Published: SpringerOpen 2024-01-01
Series:EJNMMI Research
Subjects:
Muscle denervation
Peripheral nervous system
Nicotinic acetylcholine receptor
18F-ASEM
Positron emission tomography
Online Access:https://doi.org/10.1186/s13550-024-01067-9

Internet

https://doi.org/10.1186/s13550-024-01067-9

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