A novel roadmap connecting the 1H-MRS total choline resonance to all hallmarks of cancer following targeted therapy

A novel roadmap connecting the 1H-MRS total choline resonance to all hallmarks of cancer following targeted therapy

Abstract This review describes a cellular adaptive stress signalling roadmap connecting the 1H magnetic resonance spectroscopy (MRS) total choline peak at 3.2 ppm (tCho) to cancer response after targeted therapy (TT). Recent research on cell signalling, tCho metabolism, and TT of cancer has been ret...

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Bibliographic Details
Main Authors: Egidio Iorio, Franca Podo, Martin O. Leach, Jason Koutcher, Francis G. Blankenberg, Joseph F. Norfray
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:European Radiology Experimental
Subjects:
Biomarkers
Choline
Magnetic resonance spectroscopy
Neoplasms
Unfolded protein response
Online Access:https://doi.org/10.1186/s41747-020-00192-z

Internet

https://doi.org/10.1186/s41747-020-00192-z

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