Screening and identifying a novel M-MDSCs-related gene signature for predicting prognostic risk and immunotherapeutic responses in patients with lung adenocarcinoma

Screening and identifying a novel M-MDSCs-related gene signature for predicting prognostic risk and immunotherapeutic responses in patients with lung adenocarcinoma

Background: Lung adenocarcinoma (LUAD) shows intratumoral heterogeneity, a highly complex phenomenon that known to be a challenge during cancer therapy. Considering the key role of monocytic myeloid-derived suppressor cells (M-MDSCs) in the tumor microenvironment (TME), we aimed to build a prognosti...

Full description

Bibliographic Details
Main Authors: Geng-Chong Wang, Mi Zhou, Yan Zhang, Hua-Man Cai, Seok-Theng Chiang, Qi Chen, Tian-Zhen Han, Rong-Xiu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
LUAD
M-MDSCs
prognostic model
immunotherapeutic responses
precision medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.989141/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.989141/full

Similar Items