Practical and Efficient Synthesis of α-Aminophosphonic Acids Containing 1,2,3,4-Tetrahydroquinoline or 1,2,3,4-Tetrahydroisoquinoline Heterocycles

Practical and Efficient Synthesis of α-Aminophosphonic Acids Containing 1,2,3,4-Tetrahydroquinoline or 1,2,3,4-Tetrahydroisoquinoline Heterocycles

We report here a practical and efficient synthesis of α-aminophosphonic acid incorporated into 1,2,3,4-tetrahydroquinoline and 1,2,3,4-tetrahydroisoquinoline heterocycles, which could be considered to be conformationally constrained analogues of pipecolic acid. The principal contribution of this syn...

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Bibliographic Details
Main Authors: Mario Ordóñez, Alicia Arizpe, Fracisco J. Sayago, Ana I. Jiménez, Carlos Cativiela
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
α-aminophosphonic acids
N-acyliminium ions
conformationally constrained
Online Access:http://www.mdpi.com/1420-3049/21/9/1140

Internet

http://www.mdpi.com/1420-3049/21/9/1140

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