An integrative network analysis framework for identifying molecular functions in complex disorders examining major depressive disorder as a test case

Abstract In addition to the psychological depressive phenotype, major depressive disorder (MDD) patients are also associated with underlying immune dysregulation that correlates with metabolic syndrome prevalent in depressive patients. A robust integrative analysis of biological pathways underlying...

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Bibliographic Details
Main Authors: Anup Mammen Oommen, Stephen Cunningham, Páraic S. O’Súilleabháin, Brian M. Hughes, Lokesh Joshi
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89040-7