ProCPU Is Expressed by (Primary) Human Monocytes and Macrophages and Expression Differs between States of Differentiation and Activation

ProCPU Is Expressed by (Primary) Human Monocytes and Macrophages and Expression Differs between States of Differentiation and Activation

Carboxypeptidase U (CPU, TAFIa, CPB2) is a potent attenuator of fibrinolysis that is mainly synthesized by the liver as its inactive precursor proCPU. Aside from its antifibrinolytic properties, evidence exists that CPU can modulate inflammation, thereby regulating communication between coagulation...

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Bibliographic Details
Main Authors: Karen Claesen, Joni De Loose, Pieter Van Wielendaele, Emilie De bruyn, Yani Sim, Sofie Thys, Ingrid De Meester, Dirk Hendriks
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
carboxypeptidase B2
carboxypeptidase U
gene expression
monocyte/macrophage
thrombin-activatable fibrinolysis inhibitor
Online Access:https://www.mdpi.com/1422-0067/24/4/3725

Internet

https://www.mdpi.com/1422-0067/24/4/3725

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