Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis

Cryptotanshinone alleviates lipopolysaccharide and cigarette smoke-induced chronic obstructive pulmonary disease in mice via the Keap1/Nrf2 axis

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity worldwide. Cigarette smoking, which leads to abnormalities in the airways or alveoli and persistent obstruction of the airway's flow, is a significant risk factor of COPD. Cryptotanshinone (CTS) is the active ingredient...

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Bibliographic Details
Main Authors: Hongjia Song, Lujing Jiang, Wanchun Yang, Yuxing Dai, Yao Wang, Zhuoming Li, Peiqing Liu, Jianwen Chen
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cryptotanshinone
COPD
Roflumilast
Inflammation
Lung function
Keap1
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222300896X

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http://www.sciencedirect.com/science/article/pii/S075333222300896X

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