High Level of Staufen1 Expression Confers Longer Recurrence Free Survival to Non-Small Cell Lung Cancer Patients by Promoting THBS1 mRNA Degradation

High Level of Staufen1 Expression Confers Longer Recurrence Free Survival to Non-Small Cell Lung Cancer Patients by Promoting THBS1 mRNA Degradation

Stau1 is a pluripotent RNA-binding protein that is responsible for the post-transcriptional regulation of a multitude of transcripts. Here, we observed that lung cancer patients with a high Stau1 expression have a longer recurrence free survival. Strikingly, Stau1 did not impair cell proliferation i...

Full description

Bibliographic Details
Main Authors: Florence Bonnet-Magnaval, Leïla Halidou Diallo, Valérie Brunchault, Nathalie Laugero, Florent Morfoisse, Florian David, Emilie Roussel, Manon Nougue, Audrey Zamora, Emmanuelle Marchaud, Florence Tatin, Anne-Catherine Prats, Barbara Garmy-Susini, Luc DesGroseillers, Eric Lacazette
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
SMD (Staufen-mediated mRNA decay)
tumorigenesis
thrombospondin
Online Access:https://www.mdpi.com/1422-0067/23/1/215

Internet

https://www.mdpi.com/1422-0067/23/1/215

Similar Items