Cell culture replication of a genotype 1b hepatitis C virus isolate cloned from a patient who underwent liver transplantation.

The introduction of the genotype 2a isolate JFH1 was a major breakthrough in the field of hepatitis C virus (HCV), allowing researchers to study the complete life cycle of the virus in cell culture. However, fully competent culture systems encompassing the most therapeutically relevant HCV genotypes...

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Bibliographic Details
Main Authors: George Koutsoudakis, Sofia Perez-del-Pulgar, Mairene Coto-Llerena, Patricia Gonzalez, Jakub Dragun, Laura Mensa, Gonzalo Crespo, Miguel Navasa, Xavier Forns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21887279/pdf/?tool=EBI