A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge

ABSTRACTPneumococcal disease is a major threat to public health globally, impacting individuals across all age groups, particularly infants and elderly individuals. The use of current vaccines has led to unintended consequences, including serotype replacement, leading to a need for a new approach to...

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Bibliographic Details
Main Authors: Fang-Feng Chiu, Ling-Ling Tu, Wangxue Chen, Hongyan Zhou, Bing-Sin Liu, Shih-Jen Liu, Chih-Hsiang Leng
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2272656