Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid

Hypochlorous acid (HOCl) released by activated leukocytes has been implicated in the tissue damage that characterizes chronic inflammatory diseases. In this investigation, 14 indole derivatives, including metabolites such as melatonin, tryptophan and indole-3-acetic acid, were screened for their abi...

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Bibliographic Details
Main Authors: V.F. Ximenes, I.M.M. Paino, O.M.M. de Faria-Oliveira, L.M. da Fonseca, I.L. Brunetti
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100003