Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.

Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants have not been explored in a systematic, genome-wide fashion. We carried out a...

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Bibliographic Details
Main Authors: Sunil Suchindran, David Rivedal, John R Guyton, Tom Milledge, Xiaoyi Gao, Ashlee Benjamin, Jennifer Rowell, Geoffrey S Ginsburg, Jeanette J McCarthy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2861686?pdf=render

Internet

http://europepmc.org/articles/PMC2861686?pdf=render

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