High-intensity intermittent training ameliorates methotrexate-induced acute lung injury

Abstract Inflammation and oxidative stress are recognized as two primary causes of lung damage induced by methotrexate, a drug used in the treatment of cancer and immunological diseases. This drug triggers the generation of oxidants, leading to lung injury. Given the antioxidant and anti-inflammator...

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Main Authors: Mohammad Amin Rajizadeh, Mahdiyeh Haj Hosseini, Mina Bahrami, Faegheh Bahri, Fahimeh Rostamabadi, Fatemeh Bagheri, Kayvan Khoramipour, Hamid Najafipour, Mohammad-Abbas Bejeshk
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-024-02853-w