Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase

Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase

Selenium-binding protein 1 (SELENBP1) was reported to act as a methanethiol oxidase (MTO) in humans, catalyzing the conversion of methanethiol to hydrogen peroxide, hydrogen sulfide and formaldehyde. Here, we identify copper ions as essential to this novel MTO activity. Site-directed mutagenesis of...

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Bibliographic Details
Main Authors: Thilo Magnus Philipp, Leon Gernoth, Andreas Will, Maria Schwarz, Verena Alexia Ohse, Anna Patricia Kipp, Holger Steinbrenner, Lars-Oliver Klotz
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Redox Biology
Subjects:
MTO
Methanethiol
Volatile sulfur compounds
VSC
H2S
H2O2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002082

Internet

http://www.sciencedirect.com/science/article/pii/S2213231723002082

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