Production of Bioactive Porcine Lactoferrin through a Novel Glucose-Inducible Expression System in <i>Pichia pastoris</i>: Unveiling Antimicrobial and Anticancer Functionalities

Production of Bioactive Porcine Lactoferrin through a Novel Glucose-Inducible Expression System in <i>Pichia pastoris</i>: Unveiling Antimicrobial and Anticancer Functionalities

Lactoferrin (LF) stands as one of the extensively investigated iron-binding glycoproteins within milk, exhibiting diverse biological functionalities. The global demand for LF has experienced consistent growth. Biotechnological strategies aimed at enhancing LF productivity through microbial expressio...

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Bibliographic Details
Main Authors: Chih-Ching Yen, Pei-Ying Wu, Huan Ou-Yang, Hsiao-Ling Chen, Kowit-Yu Chong, Ro-Lin Chang, Chuan-Mu Chen
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
lactoferrin
<i>G1</i> promoter
<i>Pichia pastoris</i>
fermentation
tangential-flow ultrafiltration
iron-binding
Online Access:https://www.mdpi.com/1422-0067/25/3/1818

Internet

https://www.mdpi.com/1422-0067/25/3/1818

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