Gut Microbiota Contributes to Resistance Against Pneumococcal Pneumonia in Immunodeficient Rag−/− Mice

Gut Microbiota Contributes to Resistance Against Pneumococcal Pneumonia in Immunodeficient Rag−/− Mice

Streptococcus pneumoniae causes infection-related mortality worldwide. Immunocompromised individuals, including young children, the elderly, and those with immunodeficiency, are especially vulnerable, yet little is known regarding S. pneumoniae-related pathogenesis and protection in immunocompromise...

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Bibliographic Details
Main Authors: Krysta M. Felix, Ivan A. Jaimez, Thuy-Vi V. Nguyen, Heqing Ma, Walid A. Raslan, Christina N. Klinger, Kristian P. Doyle, Hsin-Jung J. Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
microbiota
Streptococcus pneumoniae
immunocompromised
gut-lung axis
segmented filamentous bacteria (SFB)
neutrophils
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00118/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00118/full

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