Immune Checkpoint in Glioblastoma: Promising and Challenging

Immune Checkpoint in Glioblastoma: Promising and Challenging

Glioblastoma (GBM) is a severe malignant brain cancer with poor overall survival. Conventional intervention remains dismal to prevent recurrence and deterioration of GBM cell. Recent years have witnessed exciting breakthroughs in novel immune strategies, especially checkpoint inhibitors, some of whi...

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Bibliographic Details
Main Authors: Jing Huang, Fangkun Liu, Zhixiong Liu, Hui Tang, Haishan Wu, Qianni Gong, Jindong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
Glioblastoma
immunotherapy
checkpoint
CTLA-4
PD-1
PD-L1
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00242/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00242/full

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