The Cyst Epithelium in Polycystic Kidney Disease Patients Displays Normal Apical-Basolateral Cell Polarity

The Cyst Epithelium in Polycystic Kidney Disease Patients Displays Normal Apical-Basolateral Cell Polarity

The main characteristic of polycystic kidney disease is the development of multiple fluid-filled renal cysts. The discovery of mislocalized sodium-potassium pump (Na,K-ATPase) in the apical membrane of cyst-lining epithelia alluded to reversal of polarity as a possible explanation for the fluid secr...

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Bibliographic Details
Main Authors: Samuel Loft Sandegaard, Andreas Riishede, Henrik Birn, Helle Hasager Damkier, Jeppe Praetorius
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic kidney disease
cell polarity
Crumbs complex
Par complex
Scribble complex
cadherin
Online Access:https://www.mdpi.com/1422-0067/25/3/1904

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https://www.mdpi.com/1422-0067/25/3/1904

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