Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway

Abstract Objectives The study of sex differences in hyperuricemia can provide not only a theoretical basis for this clinical phenomenon but also new therapeutic targets for urate-lowering therapy. In the current study, we aimed to confirm that estradiol can promote intestinal ATP binding cassette su...

Full description

Bibliographic Details
Main Authors: Lei Liu, Tianyi Zhao, Lizhen Shan, Ling Cao, Xiaoxia Zhu, Yu Xue
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Nutrition & Metabolism
Subjects:
Online Access:https://doi.org/10.1186/s12986-021-00583-y