Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity

Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity

Despite the wealth of knowledge of transcription factors involved in lens development, little information exists about the role of DNA methylation in this process. Here, we investigated the role of DNA methylation in lens development and fiber cell differentiation using mice conditionally lacking ma...

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Bibliographic Details
Main Authors: Thanh V. Hoang, Evan R. Horowitz, Blake R. Chaffee, Peipei Qi, Rachel E. Flake, Devin G. Bruney, Blake J. Rasor, Savana E. Rosalez, Brad D. Wagner, Michael L. Robinson
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Epigenetics
Subjects:
development
dna methylation
dnmt1
dnmt3a
dnmt3b
lens
Online Access:http://dx.doi.org/10.1080/15592294.2016.1253651

Internet

http://dx.doi.org/10.1080/15592294.2016.1253651

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