Discovery and biosynthesis of macrophasetins from the plant pathogen fungus Macrophomina phaseolina

Discovery and biosynthesis of macrophasetins from the plant pathogen fungus Macrophomina phaseolina

3-Decalinoyltetramic acids (DTAs) are a class of natural products with chemical diversity and potent bioactivities. In fungal species there is a general biosynthetic route to synthesize this type of compounds, which usually features a polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) an...

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Bibliographic Details
Main Authors: Cui Yu, Lin Chen, Yang Le Gao, Jia Liu, Pei Lin Li, Ming Liang Zhang, Qin Li, Huai Dong Zhang, Man Cheng Tang, Li Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
3-Decalinoyltetramic acid
bioinformatics analysis
Macrophomina phaseolina
heterologous expression
genome mining
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1056392/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.1056392/full

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