Validation of the NAT Chagas IVD Kit for the Detection and Quantification of <i>Trypanosoma cruzi</i> in Blood Samples of Patients with Chagas Disease

Validation of the NAT Chagas IVD Kit for the Detection and Quantification of <i>Trypanosoma cruzi</i> in Blood Samples of Patients with Chagas Disease

In the absence of validated biomarkers to control the cure of Chagas disease, PCR-based diagnosis is being used as the main tool for an early indication of therapeutic failure. However, since it is considered a technique of complex reproducibility, mainly due to difficulties in establishing accurate...

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Bibliographic Details
Main Authors: Otacilio C. Moreira, Alice Gomes Fernandes, Natalia Lins da Silva Gomes, Carolina Messias dos Santos, Thiago Jacomasso, Alexandre Dias Tavares Costa, Lucas de O. Rossetti Nascimento, Alejandro Marcel Hasslocher-Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Luis Gustavo Morello, Fabricio Klerynton Marchini, Marco Aurelio Krieger, Constança Britto
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Life
Subjects:
Chagas disease
molecular diagnostics
NAT Chagas
real-time PCR
parasite load
Online Access:https://www.mdpi.com/2075-1729/13/6/1236

Internet

https://www.mdpi.com/2075-1729/13/6/1236

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